Khetha Thina
I-JDK ingumnikazi wezindawo zokukhiqiza zekilasi lokuqala kanye nempahla yokuphatha Ikhwalithi, eqinisekisa ukuhlinzekwa okuzinzile kwama-API intermediates.Ithimba lochwepheshe liqinisekisa i-R&D ngomkhiqizo.Ngokuphikisana nakho kokubili, sifuna i-CMO & CDMO emakethe yasekhaya neyamazwe ngamazwe.
Incazelo Yomkhiqizo
I-Porphyrin E6 inesakhiwo samakhemikhali esiyingqayizivele nesiyinkimbinkimbi futhi iyi-photosensitizer esekwe ku-porphyrin edlala indima ebalulekile ekuqaliseni ukusabela kwe-photodynamic.Le nhlanganisela inekhono eliyingqayizivele lokumunca ukukhanya futhi idlulise amandla, ivumela ukuthi yenze ukusabela kwe-photochemical kumaseli noma izicubu eziqondiwe.Ngalo mshini, i-porphyrin E6 ibonisa isithembiso esikhulu ekusetshenzisweni kwezokwelapha okuhlukahlukene, ikakhulukazi ekwelapheni nasekuxilongweni kwezifo ezinjengomdlavuza.
Esinye sezici ezivelele ze-porphyrin E6 yizinto zayo ezinhle kakhulu ze-optical and photophysical.Le nhlanganisela ibonisa ukumuncwa okuqinile ebangeni eliseduze ne-infrared, okuyenza ifaneleke ekungeneni kokukhanya okujulile esicutshini.Lokhu kwenza kusebenze imiphumela yokwelapha ngokunembile nangempumelelo kuyilapho kunciphisa umonakalo kumaseli anempilo.Ngaphezu kwalokho, i-porphyrin E6 inesivuno esiphezulu se-singlet oxygen quantum, eqinisekisa ukubhujiswa okuphumelelayo nokukhethiwe kwamangqamuzana omdlavuza ngaphansi kwemisebe ekhanyayo.
Ukuguquguquka kwe-Porphyrin E6 kungenye into ehlukanisayo yalo mkhiqizo.Ingasetshenziswa kokubili njenge-photosensitizer yokwelashwa kwe-photodynamic kanye ne-ejenti ehlukile yokuthwebula izithombe zokuxilonga.Izakhiwo zayo ze-fluorescent ziyenza ibe ithuluzi elihle kakhulu lokubona ngeso lengqondo kanye nokubona izimila kanye nokuqapha impendulo yokwelashwa ngokuhamba kwesikhathi.Leli khono lemisebenzi eminingi liqinisekisa ukuthi i-porphyrin E6 ayisebenzi nje kuphela ezinhlelweni zokwelapha kodwa futhi yenza umnikelo obalulekile ekutholweni kokuqala kanye nokuxilongwa okunembile.
Ngaphezu kokusebenza kwayo okukhethekile, i-Porphyrin E6 ikhiqizwa ngaphansi kwezinqubo eziqinile zokulawula ikhwalithi ukuze kuqinisekiswe ubumsulwa nokwethembeka kwayo.Itholakala ngezindlela ezihlukahlukene, okuhlanganisa izimpushana nezisombululo, ukuhlangabezana nocwaningo oluhlukene kanye nezidingo zomtholampilo.Ngokuzinza kwayo okukhethekile, i-Porphyrin E6 igcina umsebenzi wayo we-photodynamic nokusebenza ngisho nangaphansi kwezimo eziyinselele, iqinisekisa imiphumela engaguquki futhi ekwazi ukukhiqiza kabusha.