I-Palbociclib Intermediate 2-Amino-5-bromopyridine CAS No. 1072-97-5

I-Palbociclib emaphakathi 2-amino-5-bromopyridine inombolo ye-CAS 1072-97-5!Le nhlanganisela yekhwalithi ephezulu ephakathi iyingxenye ebalulekile ekuhlanganiseni kwe-palbociclib, i-cyclin-dependent kinase 4 kanye ne-6 inhibitor enamandla futhi ekhethiwe.Ifomula yamangqamuzana yalokhu okumaphakathi yi-C5H5BrN2 kanti isisindo semolekyuli singu-173.01.Isetshenziselwa ukukhiqizwa kwe-Palbociclib, umuthi obalulekile ngokumelene nomdlavuza webele.

I-Palbociclib, eyaziwa nangokuthi i-Ibrance, yaziwa kabanzi ngokusebenza kwayo ekwelapheni umdlavuza webele we-hormone receptor-positive kanye ne-HER2-negative advanced noma metastatic.Njengengxenye ebalulekile enqubweni yokukhiqiza ye-palbociclib, i-2-amino-5-bromopyridine yethu emaphakathi iyisithako esibalulekile embonini yezemithi.Ukuhlanzeka kwayo okuphezulu kanye nokwakheka kwamakhemikhali okunembayo kuyenza ibe isithako esibalulekile ekukhiqizweni kwalo muthi osindisa ukuphila.