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imikhiqizo

Fumarate vorolazan CAS No. 1260141-27-2

Incazelo emfushane:

Elinye Igama:I-Vonoprazan Fumarate (TAK-438)
I-Molecular Formula:I-C48H62N4O8
Isisindo se-Molecular:823.028


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-Vorolazan fumarate isebenza ngokuvimbela iphampu ye-proton esiswini, ngaleyo ndlela yehlise ukukhiqizwa kwe-asidi yesisu.Ngokungafani ne-proton pump inhibitors (i-PPIs) yendabuko, i-Vorolazan fumarate ibonise ukuqala ngokushesha kwesenzo kanye nokucindezelwa kwe-asidi okuqhubekayo, okuyenza ibe inketho yokwelapha ephumelela kakhulu ezigulini ezingaphenduli kahle ekwelashweni kwamanje.

Enye yezinzuzo ezinkulu ze-Vorolazan fumarate yikhono layo lokunqoba ukulinganiselwa kwezinye izidakamizwa ezinciphisa i-asidi.Indlela yayo eyingqayizivele yokusebenza ivimbela ukukhishwa kwe-asidi ngokungaguquki futhi isikhathi eside, okuholela ekulawulweni okungcono kwezimpawu nokuvimbela ukuphinda kwezilonda.Ukwengeza, i-Vorolazan fumarate ikhonjiswe ukuthi inamandla aphansi okusebenzelana nezidakamizwa, okwenza kube inketho ephephile ezigulini ezinezifo eziningi ezidinga imithi eyinkimbinkimbi.

Ezifundweni zemitholampilo, uFumarate Vorolazan ubonise ukusebenza kahle okuphakeme uma kuqhathaniswa nama-PPI akhona, ngokuqala okusheshayo kwesenzo kanye nokucindezelwa okuphezulu okuqhubekayo kwe-asidi.Lokhu kusho ukuthi iziguli zingathola ukukhululeka ngokushesha ezimpawini ezifana nesilungulela kanye ne-reflux, ukuthuthukisa izinga lempilo kanye nokunciphisa isidingo semithi yokuhlenga.

Khetha Thina

I-JDK ingumnikazi wezindawo zokukhiqiza zekilasi lokuqala kanye nempahla yokuphatha Ikhwalithi, eqinisekisa ukuhlinzekwa okuzinzile kwama-API intermediates.Ithimba lochwepheshe liqinisekisa i-R&D ngomkhiqizo.Ngokuphikisana nakho kokubili, sifuna i-CMO & CDMO emakethe yasekhaya neyamazwe ngamazwe.


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