Khetha Thina
I-JDK ingumnikazi wezindawo zokukhiqiza zekilasi lokuqala kanye nempahla yokuphatha Ikhwalithi, eqinisekisa ukuhlinzekwa okuzinzile kwama-API intermediates.Ithimba lochwepheshe liqinisekisa i-R&D ngomkhiqizo.Ngokuphikisana nakho kokubili, sifuna i-CMO & CDMO emakethe yasekhaya neyamazwe ngamazwe.
Incazelo Yomkhiqizo
I-Ethyl 2-cyanoacetate iyingxenye ebalulekile yenqubo yokukhiqiza yesidakamizwa esisebenza ngempumelelo kakhulu i-Finerenone futhi iyisihluthulelo esimaphakathi ekuhlanganiseni kwalo muthi ophumelelayo.Eyaziwa ngokusebenza kwayo okukhethekile ekwelapheni isifo sezinso esingamahlalakhona nesifo senhliziyo, i-Finerenone ithole ukunakwa okusabalele ochwepheshe bezempilo neziguli.Ngakho-ke, ukubaluleka kwe-ethyl 2-cyanoacetate akukwazi ukweqiwa njengoba idlala indima ebalulekile ekukhiqizeni lesi sidakamizwa esishintsha ukuphila.
Inombolo ye-CAS ye-ethyl 2-cyanoacetate ithi 65193-87-5.Inezinhlobonhlobo zezakhiwo ezinenzuzo ezihlukanisayo kwezinye izimaphakathi zemithi.Isakhiwo sayo samangqamuzana sinikeza ukuzinza okuhle kakhulu nokuhambisana nokusabela okuhlukahlukene kwamakhemikhali, okuqinisekisa inqubo yokwenziwa engenamthungo.I-compound ibuye ibe nokuhlanzeka okuphezulu, ikhulise ukuthembeka kwayo nokusebenza kahle.
Izikhungo zethu zokukhiqiza ezithuthukile kanye nezinyathelo eziqinile zokulawula ikhwalithi ziqinisekisa imikhiqizo enekhwalithi ephezulu ehlangabezana nezindinganiso eziqinile zomkhakha.Iqoqo ngalinye le-ethyl 2-cyanoacetate lihlolwa ngokuqinile ukuze kuqinisekiswe ukuhlanzeka, amandla nokuphepha.Siyakuqonda ukubaluleka okubalulekile kokuhlinzeka ngemikhiqizo ethembekile nephephile, ikakhulukazi embonini yezemithi lapho izimpilo zibalulekile.
Ngokungeziwe ekusebenzeni kwayo okuhle kakhulu njenge-finerenone emaphakathi, i-ethyl 2-cyanoacetate inikeza ukuguquguquka kwezinye izinhlelo zokusebenza.Izakhiwo zayo zamakhemikhali eziyingqayizivele ziyenza ibe isithako esibalulekile ekukhiqizeni izinhlanganisela ezihlukahlukene zemithi namakhemikhali amahle.I-Ethyl 2-cyanoacetate inohlu olubanzi lwezinto ezingase zisetshenziswe, yethula inqwaba yamathuba okuqamba izinto ezintsha kanye nenqubekelaphambili kukhemikhali yezokwelapha.
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