Incazelo
Inombolo ye-CAS 1378865-93-0, I-4-methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine yethu ihlanganiswe ngokucophelela futhi ihlolwe ukuze ihlangabezane nezindinganiso eziphakeme kakhulu zokuhlanzeka nekhwalithi.Idlala indima ebalulekile ekwakhiweni kwe-Alpelisib, ukwelashwa okuhlosiwe kweziguli ezinomdlavuza webele osezingeni eliphezulu noma izimila eziqinile eziphethe ukuguqulwa kwe-PIK3CA.
Lokhu okumaphakathi kwe-Alpelisib kusebenza njengebhulokhi yokwakha i-Alpelisib synthesis, evumela ukukhiqizwa kwezidakamizwa ezibonise ukusebenza okubalulekile ekuhlolweni kwemitholampilo.Isakhiwo samakhemikhali esinembile sabaphakathi bethu siqinisekisa ukuhambisana nokusebenza kwabo ngesikhathi sokuhlanganiswa, okunomthelela ekuhlanzekeni okuphezulu kanye namandla omkhiqizo wokugcina wemithi.
I-4-Methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) i-pyridine intermediate iyisici esiyinhloko ekuhlanganiseni kwamakhemikhali e-Alpelisib kanye nesihluthulelo esiphakathi kuyo yonke inqubo yokukhiqiza.Ngefomula yayo enembile yamangqamuzana nesisindo, iklanyelwe ukuhlangabezana nezidingo eziqinile zokwenziwa kwemithi, ukuqinisekisa ukuvumelana nokuthembeka ekukhiqizeni i-Alpelisib.
Khetha Thina
I-JDK ingumnikazi wezindawo zokukhiqiza zekilasi lokuqala kanye nempahla yokuphatha Ikhwalithi, eqinisekisa ukuhlinzekwa okuzinzile kwama-API intermediates.Ithimba lochwepheshe liqinisekisa i-R&D ngomkhiqizo.Ngokuphikisana nakho kokubili, sifuna i-CMO & CDMO emakethe yasekhaya neyamazwe ngamazwe.
