Inkcazo
Ifomula ye-molecular yale intermediate yi-C13H10ClN3O2S, kwaye ubunzima bayo be-molecular yi-307.755.Isakhiwo sayo esichanekileyo se-molecular senza ukuba umveliso osebenzayo kunye nococeko oluphezulu lwe-tofacitinib.Ngoko ke, i-tofacitinib ephakathi kwe-1,4-chloro-7-p-toluenesulfonyl-7H pyrrolo [2,3-d] pyrimidine yinto ebalulekileyo kwishishini lamachiza ukubonelela unyango olusebenzayo kwizifo ezizimele.
Iimveliso zethu zenziwe kusetyenziswa iinkqubo zanamhlanje zokuqinisekisa umgangatho ophezulu kunye nokuhambelana.Siyakuqonda ukubaluleka kokuba nabaphakathi abathembekileyo nabacocekileyo kwimveliso yamayeza, yiyo loo nto sizibophelele ekugcineni eyona migangatho ingqongqo ngexesha lenkqubo yethu yokuvelisa.I-tofacitinib yethu ephakathi kwe-1,4-chloro-7-p-toluenesulfonyl-7H pyrrolo [2,3-d] pyrimidine iphantsi kobunyulu obungqongqo, uzinzo kunye novavanyo lokhuseleko ukuvumela abathengi bethu ukuba baqiniseke ngokuthembeka kwe-synthesis enkulu ye-tofacitinib.
Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.