Khetha Thina
I-JDK iphethe izixhobo zokuvelisa iklasi yokuqala kunye nezixhobo zokulawula uMgangatho, oqinisekisa ukunikezelwa okuzinzile kwe-API intermediates.Iqela lobuchwephesha liqinisekisa iR&D ngemveliso.Ngokuchasene nazo zombini, sikhangela i-CMO kunye ne-CDMO kwimarike yasekhaya neyamanye amazwe.
Ingcaciso yeMveliso
I-L-proline tert-butyl ester, eyaziwa ngokuba yi-N-(pyrrolidine-2-carbonyl) -L-proline tert-butyl ester, iyinxalenye ebalulekileyo kumashishini ahlukeneyo, kubandakanywa amayeza, i-chemical synthesis, kunye nezinto eziphambili.Imveliso.Ukuguquguquka kwayo kunye noluhlu olubanzi lwezicelo kuyenza ibe yinto ebaluleke kakhulu kwiinzame zenzululwazi.
Inkqubo yokwenziwa kwemveliso ilandela eyona migangatho iphezulu yoshishino, iqinisekisa umgangatho okhethekileyo kunye nokucoceka.Ifomula ye-molecular C9H17NO2 idibanisa izinto zekhabhoni, i-hydrogen, i-nitrogen kunye ne-oksijini ukwenza i-compound enozinzo olukhethekileyo kunye nokusebenza kwakhona.Ngobunzima be-molecular 171.24, inokuphathwa ngokulula kwaye ilinganiswe ngokuchanekileyo kwindawo yebhubhoratri.
Ipropati ebalulekileyo ye-L-tert-butyl proline kukusetyenziswa kwayo ngokubanzi kwishishini lamachiza.Abaphandi basebenzisa le khompawundi ukwenza i-intermediate eyahlukeneyo yamachiza kunye nezithako ezisebenzayo zamachiza (APIs).Ulwakhiwo lwalo olukhethekileyo kunye neqela elisebenzayo livumela ukuphuhliswa kweziyobisi ezintsha ezijolise kwizifo ezithile kunye neemeko zonyango.Ukusulungeka kunye nokuchaneka kweemveliso zethu kuqinisekisa iziphumo ezichanekileyo kunye neziphumo ezithembekileyo ngexesha lophuhliso lwamachiza.
![I-Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid kunye (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8](https://cdnus.globalso.com/jdkchemicals/2R-3R-23-bis-4-methylbenzoyl-oxy-succinic-acid-and-3R-4R-N-4-dimethyl-1-phenylmethyl-3-piperidine-amine.jpg)
