Tlhaloso
E le motsoako oa bohlokoa ts'ebetsong ea tlhahiso ea Vonoprazan, Vorolazan Intermediate 5 e bapala karolo ea bohlokoa ho netefatsa katleho le botšepehi ba sehlahisoa sa ho qetela.Sebopeho sa eona se ikhethang sa lik'hemik'hale 5- (2-fluorophenyl) -N-methyl-1- (3-pyridylsulfonyl) -1H-pyrrole-3-methylamine e e khetholla ho tse ling tse lipakeng 'me e etsa hore E be motsoako oa bohlokoa bakeng sa lik'hamphani tsa meriana.
Setsing sa rona sa tlhahiso ea morao-rao, re khomarela litekanyetso tse phahameng ka ho fetisisa tsa boleng ba ho hlahisa Vorolazan Intermediate 5. Mehato ea rona e thata ea ho laola boleng e tiisa hore sehlopha ka seng se finyella litekanyetso tse thata ka ho fetisisa tsa bohloeki, botsitso le botsitso.Sena se tiisa hore bareki ba rona ba fumana lihlahisoa tseo ba ka li tšepang le ho itšetleha ka tsona bakeng sa litlhoko tsa bona tsa tlhahiso.
Khetha Rona
JDK e na le lisebelisoa tsa tlhahiso ea maemo a pele le lisebelisoa tsa taolo ea boleng, tse netefatsang phepelo e tsitsitseng ea li-intermediate tsa API.Sehlopha sa litsebi se tiisetsa R&D ka sehlahisoa.Khahlanong le bobeli, re batla CMO & CDMO 'marakeng oa lapeng le oa machabeng.
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