Tlhaloso
Alpelisib Intermediate 2-Acetyl-4-methylpyridine, karolo ea bohlokoa tlhahisong ea Alpelisib, e lebisa tsela ea PI3K 'me e bontšitse liphello tse tšepisang litekong tsa meriana bakeng sa phekolo ea lihlahala tse tiileng tse tsoetseng pele.Bohareng ka boeona bo boetse bo bontša bokhoni ba lipatlisiso le nts'etsopele ea lisebelisoa tse ling tsa meriana, e leng se etsang hore e be motsoako o fapaneng le oa bohlokoa.
Alpelisib ea rona e bohareng ea 2-acetyl-4-methylpyridine e na le foromo e nepahetseng le boima ba 'mele' me e finyella litekanyetso tse phahameng ka ho fetisisa tsa boleng le bohloeki.Re motlotlo ka ho netefatsa hore lihlahisoa tsa rona ke tsa boleng bo phahameng ka ho fetisisa le ho finyella litlhoko tse thata tsa indasteri ea meriana.Boitlamo ba rona ba bokhabane bo netefatsa hore bareki ba rona ba fumana feela li-intermediate tse ntle ho fihlela litlhoko tsa bona tsa lipatlisiso le tlhahiso.
Khetha Rona
JDK e na le lisebelisoa tsa tlhahiso ea maemo a pele le lisebelisoa tsa taolo ea boleng, tse netefatsang phepelo e tsitsitseng ea li-intermediate tsa API.Sehlopha sa litsebi se tiisetsa R&D ka sehlahisoa.Khahlanong le bobeli, re batla CMO & CDMO 'marakeng oa lapeng le oa machabeng.