Na dooro
JDK waxay leedahay tas-hiilaadka wax soo saarka heerka koowaad iyo qalabka maaraynta tayada, kaas oo hubinaya sahayda xasilloon ee dhexdhexaadiyeyaasha API.Kooxda xirfadlayaasha ahi waxay xaqiijinayaan R&D alaabta.Labada dhinacba, waxaan ka raadineynaa CMO & CDMO suuqa gudaha iyo dibadda.
Sharaxaada Alaabta
L-proline tert-butyl ester, oo sidoo kale loo yaqaan N- (pyrrolidine-2-carbonyl) -L-proline tert-butyl ester, waa qayb muhiim ah oo ka mid ah warshadaha kala duwan, oo ay ku jiraan daawooyinka, isku-darka kiimikada, iyo qalabka sare.Wax soo saar.Kala duwanaanshaheeda iyo codsiyo kala duwan ayaa ka dhigaya xarun lagama maarmaan u ah dadaallo badan oo cilmiyeed.
Habka isku-dhafka alaabtu wuxuu raacayaa heerarka warshadaha ee ugu sarreeya, isagoo hubinaya tayada gaarka ah iyo nadiifnimada.Qaaciddada kelli C9H17NO2 waxay isku daraysaa curiyayaasha kaarboon, hydrogen, nitrogen iyo ogsijiin si ay u sameeyaan xarun leh xasillooni iyo falcelin aan caadi ahayn.Miisaanka molecular ee 171.24, si fudud ayaa loo maarayn karaa oo si sax ah loogu cabbiri karaa deegaanka shaybaarka.
Hantida muhiimka ah ee L-tert-butyl proline waa isticmaalkeeda baahsan ee warshadaha dawooyinka.Cilmi-baarayaashu waxay u isticmaalaan isku-dhafkan si ay u soo saaraan dawooyin dhexdhexaad ah oo kala duwan iyo maaddooyinka daawada firfircoon (APIs).Qaab dhismeedkeeda gaarka ah iyo kooxda shaqaynaysa waxay awood u siinaysaa horumarinta dawooyin cusub oo lagu beegsanayo cudurro gaar ah iyo xaalado caafimaad.Nadiifadda iyo saxnaanta alaabtayadu waxay dammaanad qaadayaan natiijooyin sax ah iyo natiijooyin la isku halleyn karo inta lagu jiro horumarinta daroogada.
![Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid iyo (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8](https://cdnus.globalso.com/jdkchemicals/2R-3R-23-bis-4-methylbenzoyl-oxy-succinic-acid-and-3R-4R-N-4-dimethyl-1-phenylmethyl-3-piperidine-amine.jpg)
