Tsanangudzo
Yedu tofacitinib yepakati inonziwo cis-1-benzyl-4-methyl-3-methylaminopiperidine dihydrochloride uye ine CAS nhamba 1062580-52-2.Iyo yepakati ndiyo yakakosha mukugadzirwa kwe tofacitinib, mushonga unoshandiswa kurapa rheumatoid arthritis, psoriatic arthritis uye ulcerative colitis.Sevakakosha vepakati mukugadzirwa kwe tofacitinib, zvigadzirwa zvedu zvakakosha kune vaongorori vemishonga nevagadziri.
Ichi chepakati chepakati chakanyatsogadzirwa kuti chive nechokwadi chepamusoro chekuchena uye kuenderana.Neyedu-ye-ye-inogadzirwa maitiro ekugadzira uye akaomesesa emhando yekudzora matanho, unogona kuvimba kuti tofacitinib yedu yepakati inosangana nepamusoro-soro indasitiri zviyero zvekuchena uye kugadzikana.
Tofacitinib Intermediate (3R, 4R) -1-Benzyl-3- (Mmethylamino) -4-Mmethylpiperidine DiHClide ine zvakawanda zvekushandisa, zvichiita kuti ive chinhu chinokosha mukutsvakurudza kwemishonga nemakemikari.Kunyangwe iwe uri kuita tsvakiridzo yedzidzo kana kugadzira mishonga, makomisheni edu epakati anopa mhinduro dzakavimbika uye dzinodhura kune zvaunoda chaizvo.
Sarudza Isu
JDK ndiyo ine yekutanga-kirasi yekugadzira zvivakwa uye Hunhu manejimendi emidziyo, iyo inovimbisa kugadzikana kupihwa kweAPI yepakati.Chikwata chehunyanzvi chinovimbisa R&D yechigadzirwa.Kupesana nezviri zviviri, isu tiri kutsvaga CMO & CDMO mumusika wepamba uye wepasirese.