Tsanangudzo
Nhamba yeCAS 1378865-93-0, Yedu 4-methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine yakanyatsogadzirwa uye inoedzwa kuti isangane nekuchena kwepamusoro uye yemhando zviyero.Inobata basa rakakosha mukuumbwa kweAlpelisib, kurapwa kwakanangwa kune varwere vane gomarara rezamu repamusoro kana mamota akasimba ane PIK3CA mutations.
Iyi yepakati yeAlpelisib inoshanda sechivakwa cheAlpelisib synthesis, zvichiita kuti kugadzirwa kwemishonga yakaratidza kushanda kwakakosha mumakiriniki ekuedzwa.Iyo chaiyo yemakemikari chimiro chepakati pedu inovimbisa kuenderana kwavo uye kushanda kwayo panguva yekubatanidza, zvichibatsira pakuchena kwakanyanya uye simba rekupedzisira chigadzirwa chemishonga.
4-Methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine yepakati inhengo inokosha mumakemikari synthesis yeAlpelisib uye inokosha yepakati mukati mekugadzirwa kwese.Iine chaiyo mamorekuru formula uye uremu, yakagadzirirwa kuzadzisa zvinoomesesa zvinodiwa zvekugadzira mishonga, kuve nechokwadi chekuenderana uye kuvimbika mukugadzirwa kweAlpelisib.
Sarudza Isu
JDK ndiyo ine yekutanga-kirasi yekugadzira zvivakwa uye Hunhu manejimendi emidziyo, iyo inovimbisa kugadzikana kupihwa kweAPI yepakati.Chikwata chehunyanzvi chinovimbisa R&D yechigadzirwa.Kupesana nezviri zviviri, isu tiri kutsvaga CMO & CDMO mumusika wepamba uye wepasirese.
