Fa'amatalaga
O la matou tofacitinib intermediate e lauiloa foi o le cis-1-benzyl-4-methyl-3-methylaminopiperidine dihydrochloride ma e iai le numera CAS 1062580-52-2.O le intermediate o se vaega autu i le gaosiga o le tofacitinib, o se vailaʻau faʻaaogaina e togafitia ai le gasegase oona, psoriatic arthritis ma ulcerative colitis.I le avea ai ma tagata autu i le tuʻufaʻatasia o le tofacitinib, e taua tele a matou oloa i tagata suʻesuʻe ma gaosiga o vailaʻau.
O lenei mea faʻapipiʻi vaeluaga o loʻo faʻapipiʻiina ma le faʻaeteete e faʻamautinoa ai le maualuga maualuga o le mama ma le tumau.Faatasi ai ma a matou faiga faʻaonaponei faʻaonaponei faʻaonaponei ma faʻatonuga faʻatonutonu lelei, e mafai ona e faʻatuatuaina o matou tofacitinib intermediates e ausia tulaga maualuga o alamanuia mo le mama ma le mautu.
Tofacitinib Intermediate (3R, 4R) -1-Benzyl-3- (Mmethylamino) -4-Mmethylpiperidine DiHClide o loʻo i ai le tele o faʻaoga, ma avea ai ma aseta taua i suʻesuʻega vailaʻau ma vailaʻau.Pe o e fa'atautaia su'esu'ega fa'ale-a'oa'oga po'o le atina'eina o vaila'au, oa matou fa'alapotopotoga tu'ufa'atasi e maua ai tali fa'atuatuaina ma taugofie i ou mana'oga.
Filifili Matou
O le JDK o lo'o i ai le vaega muamua o le gaosiga o fale ma meafaigaluega tau pulega lelei, lea e fa'amautinoa ai le tu'uina atu o le API intermediates.'Au fa'apolofesa fa'amautinoa le R&D o le oloa.Faʻasaga ia lua, o loʻo matou suʻeina CMO & CDMO i maketi faʻapitonuʻu ma faavaomalo.