Filifili Matou
O le JDK o lo'o i ai le vaega muamua o le gaosiga o fale ma meafaigaluega tau pulega lelei, lea e fa'amautinoa ai le tu'uina atu o le API intermediates.'Au fa'apolofesa fa'amautinoa le R&D o le oloa.Faʻasaga ia lua, o loʻo matou suʻeina CMO & CDMO i maketi i totonu o le atunuʻu ma faavaomalo.
Fa'amatalaga o oloa
N-Acetyl-3-(3,5-difluorophenyl)-DL-alanine, poʻo le N-acetyl-3-DFA-DL-alanine, o se vailaʻau amino acid e gaosia.Tu'ufa'atasi mama acetyl, alanin ma difluorobenzene.O lenei fausaga mole mole tulaga ese e maua ai meatotino tulaga ese, ma avea o se meafaigaluega taua i vailaau ma suʻesuʻega kemisi.
O se tasi o uiga iloga o le N-acetyl-3-DFA-DL-alanine o lona gafatia e taofia ai enzymes patino i le tino o le tagata.O lenei fa'alavelave e mafai ona iai ni a'afiaga tetele i vaila'au, aemaise i le atina'eina o togafitiga fou mo fa'ama'i e a'afia i enzymes fa'atatau.E le gata i lea, o lona gafatia e faʻaogaina ai ni gaioiga faʻapitoa e ala i le fegalegaleai faʻatasi ma faʻamatalaga faʻapitoa e avea ai ma aseta taua i le suʻesuʻeina o auala eseese o le physiological.
O le isi itu malosi o lenei tuufaatasiga o lona gafatia e avea ma poloka fale mo le tuufaatasia o isi molelaʻau lavelave.O lona agava'a e mafai ai ona fausia ni vaega fou o vaila'au, ma fa'aaogaina tele i vaila'au kemisi ma su'esu'ega vaila'au.E mafai e tagata su'esu'e ona fa'aogaina mea fa'apitoa o le N-acetyl-3-DFA-DL-alanine e fa'atupu ai tala fou o fualaau fa'atau ma tala'aga fa'afoma'i lelei.
E le gata i lea, o le N-acetyl-3-DFA-DL-alanine e sili ona lelei le solubility i polar ma non-polar solvents, faʻafaigofie lona faʻaogaina i faiga faʻataʻitaʻiga eseese.O lona mautu i lalo o tulaga eseese e faʻamautinoa ai taunuʻuga faʻatuatuaina, faʻatagaina tagata suʻesuʻe e faia suʻesuʻega maeʻaeʻa ma maua faʻamatalaga saʻo.
O le mama ma le lelei o le N-Acetyl-3-DFA-DL-Alanine e sili ona taua, ma i le avea ai o se tagata faʻamaualuga, matou te faʻamautinoa o matou oloa e ausia tulaga maualuga.O la matou N-Acetyl-3-DFA-DL-Alanine o loʻo tuʻufaʻatasia i le faʻaaogaina o tekinolosi faʻaonaponei ma faʻatonuga faʻapitoa e faʻamautinoa ai le tumau ma le faʻamaoni i vaega uma.
