Hagati ya Tofacitinib (2R, 3R) -2,3-bis -71-8

Abahuza bacu ba tofacitinib ni ingenzi mubikorwa byo gukora tofacitinib, imiti izwi cyane ikoreshwa mu kuvura ubwoko bumwe na bumwe bwa rubagimpande.Hagati aho igira uruhare runini mu gukora tofacitinib, igira uruhare mu mikorere yayo no mu bwiza.Binyuze kuri (2R, 3R) -2,3-bis ibicuruzwa byemeza synthesis ya tofacitinib yujuje ubuziranenge yujuje kandi irenze ibipimo byinganda.

Inzira ya molekuline nuburemere bwa tofacitinib hagati yacu yerekana ubuziranenge bwayo nimbaraga zayo, bigatuma iba ikintu cyizewe mubikorwa byo gukora imiti.Hamwe nibikoresho byapimwe neza, iyi intera iremeza guhuza no gukora neza ibicuruzwa byanyuma, tofacitinib.Imiterere ya molekuline nayo igira uruhare muri tofacitinib muri rusange no kubaho neza, bikomeza kuba byiza kandi byizewe mugihe kirekire.