Sankhani Ife
JDK ili ndi malo opangira kalasi yoyamba ndi zida zowongolera Ubwino, zomwe zimatsimikizira kukhazikika kwapakati pa API.Gulu la akatswiri limatsimikizira R&D za malonda.Motsutsa zonsezi, tikufunafuna CMO & CDMO pamsika wapakhomo ndi wapadziko lonse lapansi.
Mafotokozedwe Akatundu
N-Acetyl-3-(3,5-difluorophenyl) -DL-alanine, kapena kungoti N-acetyl-3-DFA-DL-alanine, ndi yopangidwa ndi amino acid.Amaphatikiza mphete za acetyl, alanine ndi difluorobenzene.Mamolekyu apadera ameneŵa amaupatsa mphamvu zapadera, kuupangitsa kukhala chida chofunika kwambiri pa kafukufuku wamankhwala ndi mankhwala.
Chimodzi mwazinthu zosiyanitsa za N-acetyl-3-DFA-DL-alanine ndikutha kuletsa ma enzyme ena m'thupi la munthu.Kulepheretsa kumeneku kungakhale ndi zotsatirapo zazikulu pazamankhwala, makamaka pakupanga mankhwala atsopano a matenda omwe amakhudzidwa ndi ma enzyme omwe akuwongoleredwa.Kuphatikiza apo, kuthekera kwake kosinthira njira zina zachilengedwe polumikizana ndi ma receptor apadera kumapangitsa kuti ikhale yofunikira pakuwerenga njira zosiyanasiyana zathupi.
Chinthu chinanso chochititsa chidwi cha mankhwalawa ndi kuthekera kwake monga chomangira cha kaphatikizidwe ka mamolekyu ena ovuta.Kusinthasintha kwake kumapangitsa kuti pakhale mankhwala atsopano, zomwe zimapangitsa kuti zikhale zothandiza kwambiri pamankhwala amankhwala komanso kupeza mankhwala.Ofufuza amatha kugwiritsa ntchito zida zapadera za N-acetyl-3-DFA-DL-alanine kuti apange anthu omwe akufuna kukhala ndi mankhwala omwe ali ndi mbiri yabwino yazamankhwala.
Komanso, N-acetyl-3-DFA-DL-alanine ali kwambiri solubility zosiyanasiyana polar ndi sanali polar solvents, kutsogolera ntchito yake mu njira zoyesera zosiyanasiyana.Kukhazikika kwake pansi pazikhalidwe zosiyanasiyana kumatsimikizira zotsatira zodalirika, kulola ochita kafukufuku kuti ayese bwino ndikupeza deta yolondola.
Kuyera ndi khalidwe la N-Acetyl-3-DFA-DL-Alanine ndizofunikira kwambiri, ndipo monga ogulitsa onyada, timatsimikizira kuti katundu wathu amakwaniritsa miyezo yapamwamba kwambiri.N-Acetyl-3-DFA-DL-Alanine yathu imapangidwa pogwiritsa ntchito ukadaulo wamakono komanso njira zowongolera zowongolera kuti zitsimikizire kusasinthika komanso kudalirika pagulu lililonse.
