Tofacitinib Intermediate (2R, 3R) -2,3-bis [(4-methylbenzoyl) oxy] succinic acid thiab (3R, 4R) - N, 4-dimethyl-1- (phenylmethyl) -3-piperidine amine CAS No. 477600 -71-8

Peb cov tofacitinib intermediates yog qhov tseem ceeb hauv kev tsim cov txheej txheem ntawm tofacitinib, cov tshuaj paub zoo siv los kho qee hom mob caj dab.Qhov nruab nrab no ua lub luag haujlwm tseem ceeb hauv kev tsim cov tofacitinib, pab txhawb rau nws cov txiaj ntsig thiab zoo.Ntawm (2R,3R)-2,3-bis[(4-methylbenzoyl)oxy] succinic acid thiab (3R,4R)-N,4-dimethyl-1-(phenylmethyl) - Kev sib xyaw ua ke ntawm 3-piperidinamines, peb cov khoom lag luam ua kom cov synthesis ntawm cov tofacitinib zoo uas ua tau raws li cov qauv kev lag luam.

Cov mis mos molecular thiab qhov hnyav ntawm peb cov tofacitinib nruab nrab qhia tau hais tias nws cov purity thiab potency, ua rau nws ib tug txhim khu kev qha tivthaiv ntawm kev tsim tshuaj.Nrog nws cov khoom xyaw ua tib zoo ntsuas, qhov nruab nrab no lav qhov sib xws thiab kev ua tau zoo ntawm cov khoom kawg, tofacitinib.Nws cov khoom molecular kuj pab txhawb rau tofacitinib qhov ruaj khov thiab lub neej txee, kom ntseeg tau tias nws tseem siv tau thiab txhim khu kev qha nyob rau lub sijhawm ntev.