Kev piav qhia
CAS tus lej 1378865-93-0, Peb 4-methyl-2-(1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine yog ua tib zoo tsim thiab sim ua kom tau raws li cov qauv purity thiab zoo tshaj plaws.Nws ua lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm Alpelisib, txoj kev kho mob rau cov neeg mob uas mob qog noj ntshav siab lossis cov qog nqaij hlav harboring PIK3CA kev hloov pauv.
Qhov no Alpelisib nruab nrab ua haujlwm ua lub tsev thaiv rau Alpelisib synthesis, ua rau kev tsim cov tshuaj uas tau pom tias muaj txiaj ntsig zoo hauv kev sim tshuaj.Cov qauv tshuaj muaj tseeb ntawm peb cov intermediates ua kom lawv cov kev sib raug zoo thiab kev ua tau zoo thaum lub sijhawm sib txuas, ua rau muaj kev coj dawb huv thiab muaj zog ntawm cov khoom siv tshuaj zaum kawg.
4-Methyl-2-(1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine intermediate yog ib qho tseem ceeb hauv cov tshuaj synthesis ntawm Alpelisib thiab ib qho tseem ceeb nruab nrab ntawm tag nrho cov txheej txheem ntau lawm.Nrog nws cov mis molecular meej thiab qhov hnyav, nws yog tsim los ua kom tau raws li cov kev cai nruj ntawm kev tsim tshuaj, ua kom muaj kev sib luag thiab kev ntseeg siab hauv Alpelisib ntau lawm.
Xaiv Peb
JDK muaj cov chaw tsim khoom thawj zaug thiab cov cuab yeej tswj kev ua haujlwm zoo, uas ua kom muaj kev ruaj khov ntawm API intermediates.Pab neeg tshaj lij paub tseeb R & D ntawm cov khoom.Tawm tsam ob qho tib si, peb tab tom nrhiav rau CMO & CDMO hauv kev lag luam hauv tsev thiab thoob ntiaj teb.
