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ʻO ka helu CAS 1378865-93-0, ʻO kā mākou 4-methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine i hoʻopaʻa pono ʻia a hoʻāʻo ʻia e hoʻokō i nā kūlana maʻemaʻe kiʻekiʻe a me ka maikaʻi.He kuleana koʻikoʻi ia i ka synthesis o Alpelisib, kahi lāʻau lapaʻau i manaʻo ʻia no nā poʻe maʻi me ka maʻi maʻi umauma kiʻekiʻe a i ʻole nā maʻi koko paʻa e mālama ana i nā mutations PIK3CA.
Ke lawelawe nei kēia kikowaena Alpelisib ma ke ʻano he hale kūkulu no Alpelisib synthesis, hiki ke hana i nā lāʻau lapaʻau i hōʻike i ka pono nui i nā hoʻokolohua lapaʻau.ʻO ka hoʻolālā kemika pololei o kā mākou mea waena e hōʻoia i ko lākou kūpono a me ka pono i ka wā synthesis, e hāʻawi ana i ka maʻemaʻe kiʻekiʻe a me ka ikaika o ka huahana lāʻau lapaʻau hope loa.
ʻO 4-Methyl-2-(1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine intermediate he mea nui ia i ka synthesis chemical o Alpelisib a me kahi mea koʻikoʻi i loko o ke kaʻina hana holoʻokoʻa.Me kona ʻano molekala pololei a me ke kaumaha, ua hoʻolālā ʻia e hoʻokō i nā koi koʻikoʻi o ka hana lāʻau lapaʻau, e hōʻoia ana i ka paʻa a me ka hilinaʻi i ka hana ʻo Alpelisib.
E koho iā mākou
Loaʻa iā JDK nā hale hana papa mua a me nā lako hoʻokele maikaʻi, e hōʻoiaʻiʻo ana i ka lako paʻa o nā kikowaena API.Hōʻoia ka hui ʻoihana i ka R&D o ka huahana.E kūʻē i nā mea ʻelua, ke ʻimi nei mākou iā CMO & CDMO ma ka mākeke kūloko a me ka honua.
